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Phagocytosis Assays

Phagocytosis in mammals serves as an important first line defense mechanism against invading pathogens. It is also essential for continuous clearance of dying cells, tissue remodeling, and acquisition of nutrients for some cells. Phagocytosis is a specific form of endocytosis initiated by recognition and binding of foreign particles by cell surface receptors, followed by their engulfment, and formation of phagosomes. Maturing phagosomes transform to phagolysosomes which destroy the pathogen through enzymes and toxic peroxides.

PromoKine‚Äôs Phagocytosis Assay Kits utilize pre-labeled E. coli or Zymosan particles as a tool for rapid and accurate detection and quantification of in vitro phagocytosis by fluorescent microscope, spectrophotometer or flow cytometry. Our kits provides a robust screening system for activators and/or inhibitors of phagocytosis and Toll-like Receptor (TLR) ligands.
E. coli and other bacterial strains are often used as a pathogen in phagocytosis assays. Our Phagocytosis Assay Kits (E. coli) utilize heat-killed, red or green-fluorescently pre-labeled E. coli particles.
Zymosan prepared from yeast cell wall (S. cerevisiae) consists of protein-carbohydrate complexes and is frequently used as a pathogen in phagocytosis assays. PromoKine's Phagocytosis Assay Kits (Zymosan) utilize red or green-fluorescently pre-labeled Zymosan particles.

References, Questions & Answers

Product Name Description Size Catalog Number Information Prices
Phagocytosis Assay Kit (Green E. coli) For rapid and accurate detection and quantification of in vitro phagocytosis by fluorescent microscope, spectrophotometer or flow cytometry. 100 assays PK-CA577-K963 click to select country
Phagocytosis Assay Kit (Red E. coli) For rapid and accurate detection and quantification of in vitro phagocytosis by fluorescent microscope, spectrophotometer or flow cytometry. 100 assays PK-CA577-K964 click to select country
Phagocytosis Assay Kit (Green Zymosan) For rapid and accurate detection and quantification of in vitro phagocytosis by fluorescent microscope, spectrophotometer or flow cytometry. 100 assays PK-CA577-K397 click to select country
Phagocytosis Assay Kit (Red Zymosan) For rapid and accurate detection and quantification of in vitro phagocytosis by fluorescent microscope, spectrophotometer or flow cytometry. 100 assays PK-CA577-K398 click to select country