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Intracellular Calcium Indicators

Applications

  • Intracellular calcium signalling studies
  • Investigation of signal transduction and apoptotic cascades
  • Neuroscience research

Benefits

  • High quality and sensitivity
  • Derivatives for special applications available
  • Compatible with standard fluorescent equipment

Calcium ions are important second messengers in cells. They are involved in muscle contraction, nerve signal transmission, immune cell activation, hormone secretion, etc.
Fluorescent calcium indicators selectively bind to calcium ions and show a spectral response upon binding Ca2+, i.e., fluorescence intensity or wavelength are altered. This shift of fluorescence wavelength and change of intensity upon calcium chelation can be monitored using fluorescence microscopy.

PromoKine offers a wide range of fluorescent calcium indicators for sensitively detecting changes in the intracellular Ca2+ concentration, including Fura-2, Fluo-3, Rhod-2, and Indo-1 (as cell-impermeable salts or cell-permeable AM esters) as well as their low-affinity derivatives Fura-2FF, Fluo-3FF, and Indo-1FF which are particularly useful for certain applications (e.g. spatial and functional characterization of Ca2+ stores or detection of NMDA-induced neuronal Ca2+ fluxes).

Moreover, we are also providing a range of coelenterazine derivatives which are effective luminescent calcium indicators.

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Product Name Description Size Catalog Number Information Prices
Fura-2FF AM Difluorinated derivative of Fura-3 (acetoxymethyl ester) 500 µg PK-CA578-F1044 click to select country
Fura-2FF (K+ Salt) Difluorinated derivative of Fura-2(K+ Salt) 500 µg PK-CA578-F1046 click to select country
FFP-18 AM Fluorescent near-membrane calciumindicator (Fura-derivative; acetoxymethyl ester) 500 µg PK-CA578-F1052 click to select country
FIP-18 AM Fluorescent near-membrane calcium indicator (Indo-derivative; acetoxymethyl ester) 500 µg PK-CA578-F1054 click to select country
Indo-1FF AM Difluorinated derivative of Indo-1(acetoxymethyl ester) 500 µg PK-CA578-I1084 click to select country
Indo-1FF (K+ Salt) Difluorinated derivative of Indo-1(K+ Salt) 500 µg PK-CA578-I1086 click to select country
5,5'-dibromo-Bapta,tetrapotassium salt 100 mg PK-CA707-50004 click to select country
5,5i-difluoro-Bapta AM 25 mg PK-CA707-50005 click to select country
5,5i-difluoro-Bapta (tetrapotassium salt) 100 mg PK-CA707-50006 click to select country
Fluo-3 (pentaammonium salt) 1 mg PK-CA707-50010 click to select country
Fluo-3 (pentapotassium salt) 1 mg PK-CA707-50011 click to select country
Fluo-3 (pentasodium salt) 1 mg PK-CA707-50012 click to select country
Fluo-3 AM (special packaging) 10 x 100 µg PK-CA707-50013 click to select country
Fluo-3 AM 1 mg PK-CA707-50014 click to select country
Fluo-3 AM Solution(1 mM in anhydrous DMSO) 1 ml PK-CA707-50015 click to select country
Fluo-3 AM (special packaging) 20 x 50 µg PK-CA707-50016 click to select country
Rhod-2(triammonium salt) 1 mg PK-CA707-50020 click to select country
Rhod-2(tripotassium salt) 1 mg PK-CA707-50021 click to select country
Rhod-2(trisodium salt) 1 mg PK-CA707-50022 click to select country
Rhod-2 AM (special packaging) 10 x 100 µg PK-CA707-50023 click to select country
Rhod-2 AM 1 mg PK-CA707-50024 click to select country
Fura-2 AM Solution(1 mM in anhydrous DMSO) 1 ml PK-CA707-50029 click to select country
Fura-2(pentaammonium salt) 1 mg PK-CA707-50030 click to select country
Fura-2(pentapotassium salt) 1 mg PK-CA707-50031 click to select country
Fura-2(pentasodium salt) 1 mg PK-CA707-50032 click to select country
Fura-2 AM (special packaging) 10 x 100 µg PK-CA707-50033 click to select country
Fura-2 AM (special packaging) 20 x 50 µg PK-CA707-50033-1 click to select country
Fura-2 AM 1 mg PK-CA707-50034 click to select country
Furaptra, tetrapotassium salt 1 mg PK-CA707-50035 click to select country
Furaptra, tetrasodium salt 1 mg PK-CA707-50036 click to select country
Furaptra, AM ester(special packaging) 10 x 100 µg PK-CA707-50037 click to select country
Furaptra, AM ester 1 mg PK-CA707-50038 click to select country
Furaptra, AM ester(special packaging) 20 x 50 µg PK-CA707-50039 click to select country
Indo-1 (pentaammonium salt) 1 mg PK-CA707-50040 click to select country
Indo-1 (pentapotassium salt) 1 mg PK-CA707-50041 click to select country
Indo-1 (pentasodium salt) 1 mg PK-CA707-50042 click to select country
Indo-1 AM (special packaging) 10 x 100 µg PK-CA707-50043 click to select country
Indo-1 AM (special packaging) 20 x 50 µg PK-CA707-50043-1 click to select country
Indo-1 AM 1 mg PK-CA707-50044 click to select country
Bis-Fura-2, hexapotassium salt 1 mg PK-CA707-50045 click to select country


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Calcium Chelators

Product Name Description Size Catalog Number Information Prices
Bapta-FF (free acid) Difluorinated derivative of BAPTA(free acid) 10 mg PK-CA578-B1091 click to select country
Bapta-FF AM Difluorinated derivative of BAPTA(acetoxymethyl ester) 10 mg PK-CA578-B1093 click to select country
Bapta AM 25 mg PK-CA707-50000 click to select country
Bapta AM (special packaging) 20 x 1 mg PK-CA707-50000-1 click to select country
Bapta (tetracesium salt) 1 g PK-CA707-50001 click to select country
Bapta(tetrapotassium salt) 1 g PK-CA707-50002 click to select country
Bapta(tetrasodium salt) 1 g PK-CA707-50003 click to select country
5,5'-dibromo-Bapta,tetrapotassium salt 100 mg PK-CA707-50004 click to select country
5,5'-dimethyl BAPTA, AM ester 25 mg PK-CA707-50007 click to select country
5,5'-dimethyl BAPTA,tetrapotassium salt 100 mg PK-CA707-50008 click to select country


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Luminescent Calcium Indicators

Product Name Description Size Catalog Number Information Prices
Coelenterazine (native) Coelenterazine (native) luminescent calcium indicator and Renilla luciferase substrate 50 µg PK-CA707-10110 click to select country
Coelenterazine h Coelenterazine derivative; luminescent calcium indicator and Renilla luciferase substrate 50 µg PK-CA707-10111 click to select country
Coelenterazine cp Coelenterazine derivative; luminescent calcium indicator and Renilla luciferase substrate 50 µg PK-CA707-10112 click to select country
Coelenterazine hcp Coelenterazine derivative; luminescent calcium indicator and Renilla luciferase substrate 50 µg PK-CA707-10113 click to select country
Coelenterazine f Coelenterazine derivative; luminescent calcium indicator and Renilla luciferase substrate 50 µg PK-CA707-10114 click to select country
Coelenterazine n Coelenterazine derivative; luminescent calcium indicator and Renilla luciferase substrate 50 µg PK-CA707-10115 click to select country
Coelenterazine ip Coelenterazine derivative; luminescent calcium indicator and Renilla luciferase substrate 50 µg PK-CA707-10116 click to select country
Coelenterazine fcp Coelenterazine derivative; luminescent calcium indicator and Renilla luciferase substrate 50 µg PK-CA707-10117 click to select country
Coelenterazine i Coelenterazine derivative; luminescent calcium indicator and Renilla luciferase substrate 50 µg PK-CA707-10121 click to select country
Coelenterazine, 2-methyl Coelenterazine derivative; luminescent calcium indicator and Renilla luciferase substrate 50 µg PK-CA707-10122 click to select country
Coelenterazine Sampler Kit 9 x 2Coelenterazine and derivatives thereof 9 x 25 µg PK-CA707-10123 click to select country
Coelenterazine 400a (also known as DeepBlue C) 50 µg PK-CA707-10125 click to select country


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Other Intracellular Indicators

Applications

  • pH determination
  • Iron, zinc, and chloride ion detection

Benefits

  • High quality and sensitivity

In addition to our calcium probes, PromoKine also offers pH indicators as well as indicators for iron, zinc and chloride ion detection.

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Product Name Description Size Catalog Number Information Prices
BCECF AM Solution(1 mg/ml in dry DMSO) 1 ml PK-CA707-51009 click to select country
BCECF 1 mg PK-CA707-51010 click to select country
BCECF AM (special packaging) 10 x 100 µg PK-CA707-51011 click to select country
BCECF AM (special packaging) 20 x 50 µg PK-CA707-51011-1 click to select country
BCECF AM 1 mg PK-CA707-51012 click to select country
5-(and-6)-Carboxyfluorescein 100 mg PK-CA707-51013 click to select country
5(6)-CFDA 100 mg PK-CA707-51014 click to select country
5-(and-6)-Carboxy-2',7'- dichlorofluorescein 200 mg PK-CA707-51015 click to select country
5-(and-6)-Carboxy-2',7'- dichlorofluorescein diacetate 100 mg PK-CA707-51016 click to select country
5-Carboxy-2',7'- dichlorofluorescein 100 mg PK-CA707-51017 click to select country
5-CFDA 100 mg PK-CA707-51018 click to select country
5-FAM 100 mg PK-CA707-51019 click to select country
6-FAM 100 mg PK-CA707-51020 click to select country
6-CFDA 100 mg PK-CA707-51021 click to select country
Flubida-2 5 mg PK-CA707-51022 click to select country
5-Carboxy-2',7'- dichlorosulfonefluorescein 10 mg PK-CA707-51023 click to select country
SPQ 50 mg PK-CA707-52010 click to select country
MQAE 100 mg PK-CA707-52011 click to select country
Zinquin, ethyl ester 5 mg PK-CA707-52020 click to select country
Zinquin, free acid 5 mg PK-CA707-52022 click to select country
TPEN 100 mg PK-CA707-59003 click to select country
5-(and-6)-Carboxy-2',7'- dichlorofluorescein diacetate succinimidyl ester 25 mg PK-CA707-90040 click to select country
5(6)-CFDA, SE (CFSE) 25 mg PK-CA707-90041 click to select country


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Related Products

Product Name Description Size Catalog Number Information Prices
Ionomycin (free acid) 5 mg PK-CA577-1565-5 click to select country
Ionomycin (Calcium salt) 5 mg PK-CA577-1566-5 click to select country
Flubi-2 5 mg PK-CA707-51024 click to select country
Pluronic F-127 1 g PK-CA707-59000 click to select country
A-23187 Free Acid A-23187 Free Acid (Calcimycin; or Calcium Ionophore III) 1 mg PK-CA707-59001 click to select country
EDC (EDAC) EDAC (1-(3-dimethylaminopropyl-3- ethylcarbodiimide, hydrochloride)) 100 mg PK-CA707-59002 click to select country
Pluronic F-127(20% solution in DMSO) 1 ml PK-CA707-59004 click to select country
Pluronic F-127 (10% solution in H2O) 30 ml PK-CA707-59005 click to select country
4-Bromo A-23187 free acid 1 mg PK-CA707-59006 click to select country
Calcium Calibration Buffer Kit 2 x 50 ml PK-CA707-59100 click to select country
DMSO, anhydrous 10 ml PK-CA707-90082 click to select country


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