Products

Cell Migration/Chemotaxis Assay Kits

Cell migration is a highly integrated, multi-step process by which cells move from one location to another. Cell motility is observed in unicellular organisms and is essential for the development and maintenance of multicellular organisms. Cells often migrate in response to specific external stimuli, including chemical and mechanical signals.
As cell migration plays an important role in various cellular processes such as angiogenesis, embryonic development, and the immune response, alterations in this process can lead to a number of pathologies including vascular disease, tumor formation and metastasis, atherosclerosis, arthritis and cognitive impairment.

PromoKine’s Cell Migration/Chemotaxis and Cell Invasion Assay Kits are easy to use, sensitive and adaptable to high-throughput systems. The Cell Migration Assay Kits utilize a Boyden chamber, where the cells migrate through a semi-permeable membrane (available with three different pore sizes) in response to stimulatory or inhibitory compounds. Cell migra­tion can be analyzed directly by reading fluorescence (Ex/Em = 530 nm/590nm) in a plate reader.  

Selection Guide Cell Migration & Cell Invasion Assays

Principle of PromoKine‘s Cell Migration Assays. 1) Plate well with insert; cell suspension in top chamber, media with or without chemoattractants in bottom chamber. 2) Migratory cells pass through a semi-permeable polycarbonate membrane. Non-migratory cells stay in the top chamber. 3) Migratory cells cling to the outer side of the top chamber and are dissociated from the porous membrane into the media of the bottom chamber. 4) Dissociated, migratory cells from bottom chamber are fluorescently stained and quantified using a fluorescence plate reader.
Product Name Description Size Catalog Number Information Prices
Cell Migration/Chemotaxis Assay Kit (8 µm, 96-well) Highly sensitive and quantitative fluorometric assay to measure cell migration/chemotaxis in response to stimuli. 100 assays PK-CA577-K906 click to select country
Cell Migration/Chemotaxis Assay Kit (8 µm, 24-well) Highly sensitive and quantitative fluorometric assay to measure cell migration/chemotaxis in response to stimuli. 12 assays PK-CA577-K909 click to select country
Cell Migration/Chemotaxis Assay Kit (5 µm, 96-well) Highly sensitive and quantitative fluorometric assay to measure cell migration/chemotaxis in response to stimuli. 100 assays PK-CA577-K907 click to select country
Cell Migration/Chemotaxis Assay Kit (5 µm, 24-well) Highly sensitive and quantitative fluorometric assay to measure cell migration/chemotaxis in response to stimuli. 12 assays PK-CA577-K910 click to select country
Cell Migration/Chemotaxis Assay Kit (3 µm, 96-well) Highly sensitive and quantitative fluorometric assay to measure cell migration/chemotaxis in response to stimuli. 100 assays PK-CA577-K908 click to select country
Cell Migration/Chemotaxis Assay Kit (3 µm, 24-well) Highly sensitive and quantitative fluorometric assay to measure cell migration/chemotaxis in response to stimuli. 12 assays PK-CA577-K911 click to select country