Products

Applications

  • Induction of apoptotic effects
  • Ideally suited for use with diverse apoptosis detection systems

Features

  • high quality
  • ready-to-use

Apoptosis Inducers

PromoKine offers a selected choice of high quality apoptosis inducers, partially in ready-to-use form or in a convenient set. The apoptosis inducers are well characterized and effective e.g. in disrupting mitochondrial transmembrane potential and activating caspases as well as inducing phosphatidyl-serine (PS) exposure, DNA fragmentation and other apoptotic characteristics. All inducers are ideally suited for use with various of PromoKine's apoptosis detection systems. Diverse high quality antibodies, cytokines and growth factors  that are involved in apoptosis as well as Apoptosis ELISAs are also available separately.

References, Questions & Answers

Product Name Description Size Catalog Number Information Prices
Carboplatin cis-Diammine(1,1-cyclobutanedicarboxylato) platinum 100 mg PK-CA577-1553-100 click to select country
Mifepristone 11ß-(4-Dimethyl­amino)­phenyl-17ß-hydroxy-17-(1-propynyl)­estra-4,9-dien-3-one, RU-486, RU-38486 50 mg PK-CA577-1561-50 click to select country
Actinomycin D Potent inducer of apoptosis in many cell lines 50 mg PK-CA577-1036-50MG click to select country
Actinomycin D Potent inducer of apoptosis in many cell lines 5 mg PK-CA577-1036-5MG click to select country
Actinomycin D (10 mM) Ready-to-use apoptosis inducer 50 µl PK-CA577-1036-50 click to select country
Anisomycin Activator of p54 and MAP kinases; induces apoptosis e.g. in the human monoblastoid cell line 10 mg PK-CA577-1549-10 click to select country
Apoptosis Inducer Set Contains 5 ready-to-use apoptosis inducers (Actinomycin D, Camptothecin, Cycloheximide, Dexamethasone, Etoposide) in a kit format 1 kit PK-CA577-K121-5 click to select country
Betulinic acid Anti-tumor and anti-HIV agent that induces apoptosis 25 mg PK-CA577-1552-25 click to select country
Brefeldin A Induces apoptosis via caspase activation 5 mg PK-CA577-1560-5 click to select country
Camptothecin Induces apoptosis e.g. in Jurkat, osteosarcoma and hepatoma cells 500 mg PK-CA577-1039-500MG click to select country
Camptothecin Induces apoptosis e.g. in Jurkat, osteosarcoma and hepatoma cells 50 mg PK-CA577-1039-50MG click to select country
Camptothecin (2 mM) Ready-to-use apoptosis inducer 1 ml PK-CA577-1039-1 click to select country
Colchicine Induce apoptosis e.g. in PC-12 cells and cerebellar granule cells 1 g PK-CA577-1519 click to select country
Cycloheximide Induces apoptosis in a variety of cells but can also delay or inhibit apoptosis by other agents 1 g PK-CA577-1041-1G click to select country
Cycloheximide (100 mM) Ready-to-use apoptosis inducer 1 ml PK-CA577-1041-1 click to select country
Daunorubicin.HCl Induces DNA single strand breaks and apoptosis e.g. in HeLaS3 tumor cells 10 mg PK-CA577-1524-10 click to select country
Dexamethasone Induces apoptosis e.g. in human thymocytes 10 g PK-CA577-1042-10G click to select country
Dexamethasone Induces apoptosis e.g. in human thymocytes 1 g PK-CA577-1042-1G click to select country
Dexamethasone (10 mM) Ready-to-use apoptosis inducer 1 ml PK-CA577-1042-1 click to select country
Doxorubicin.HCl Anti-tumor antibiotic that induces apoptosis 5 mg PK-CA577-1527-5 click to select country
Etoposide Induces apoptosis e.g. in human T cells, mouse thymocytes, and HL-60 human leukemia cells 250 mg PK-CA577-1043-250MG click to select country
Etoposide Induces apoptosis e.g. in human T cells, mouse thymocytes, and HL-60 human leukemia cells 25 mg PK-CA577-1043-25MG click to select country
Etoposide (10 mM) Ready-to-use apoptosis inducer 100 µl PK-CA577-1043-100 click to select country
Genistein Produces cell cycle arrest and apoptosis (>99% pure) 10 mg PK-CA577-1533-10 click to select country
Genistein Produces cell cycle arrest and apoptosis (>99% pure) 100 mg PK-CA577-1533-100 click to select country
Ionomycin (Calcium salt) 5 mg PK-CA577-1566-5 click to select country
Ionomycin (free acid) 5 mg PK-CA577-1565-5 click to select country
Mitomycin C Inhibitor of DNA synthesis, nuclear division. Induces apoptosis in cancer cells. 10 mg PK-CA578-M1108-10 click to select country
Mitomycin C Inhibitor of DNA synthesis, nuclear division. Induces apoptosis in cancer cells. 100 mg PK-CA578-M1108-100 click to select country
Mitomycin C Inhibitor of DNA synthesis, nuclear division. Induces apoptosis in cancer cells. 5 mg PK-CA578-M1108-5 click to select country
Okadaic acid Induces apoptosis e.g. in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells, but inhibits glucocorticoid-induced apoptosis in T-cell hybridomas 25 µg PK-CA577-1543-25 click to select country
Phorbol-12-myristate 13-acetate (PMA) Inhibits apoptosis induced by the Fas antigen, but induces apoptosis e.g. in HL-60 promyelocytic leukemia cells 5 mg PK-CA577-1544-5 click to select country
Rapamycin Reported to induce apoptosis in a murine B cell line (>99% pure) 5 mg PK-CA577-1568-5 click to select country
Rapamycin Reported to induce apoptosis in a murine B cell line (>99% pure) 50 mg PK-CA577-1568-50 click to select country
Rosiglitazone Induces apoptosis in various cells, e.g. in vascular smooth muscle cells 100 mg PK-CA577-1559-100 click to select country
Rosiglitazone Induces apoptosis in various cells, e.g. in vascular smooth muscle cells 5 mg PK-CA577-1559-5 click to select country
Staurosporine Potent apoptosis inducer 100 µg PK-CA577-1048-010 click to select country
Staurosporine Potent apoptosis inducer 1 mg PK-CA577-1048-1 click to select country
Tamoxifen citrate Induces apoptosis e.g. in human malignant glioma cell lines 1 g PK-CA577-1551 click to select country
Thapsigargin Induces apoptosis in rat thymocytes and in human hepatoma cells (>99% pure) 1 mg PK-CA577-1558-1 click to select country
Tyrphostin AG 1295 Specific and potent inhibitor of JAK2 protein tyrosine kinase, EGF receptor autophosphorylation, DNA synthesis and cell growth (>99%) 5 mg PK-CA577-1571-5 click to select country
Tyrphostin AG 490 Specific and potent inhibitor of JAK2 protein tyrosine kinase, EGF receptor autophosphorylation, DNA synthesis and cell growth (>99%) 5 mg PK-CA577-1570-5 click to select country