Products

Apoptosis Inducers

PromoKine offers a selected choice of high quality apoptosis inducers, partially in ready-to-use form or in a convenient set. The apoptosis inducers are well characterized and effective e.g. in disrupting mitochondrial transmembrane potential and activating caspases as well as inducing phosphatidyl-serine (PS) exposure, DNA fragmentation and other apoptotic characteristics. All inducers are ideally suited for use with various of PromoKine's apoptosis detection systems. Diverse high quality antibodiescytokines and growth factors  that are involved in apoptosis as well as Apoptosis ELISAs are also available separately.

References, Questions & Answers

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Product Name Description Size Catalog Number Information Prices
24(S)-Hydroxycholesterol An important cholesterol metabolite that has been shown to induce cell death in neuroblastoma cells, possibly via a necroptosis pathway. 1 mg PK-CA577-2411-1 click to select country

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Product Name Description Size Catalog Number Information Prices
Actinomycin D Potent inducer of apoptosis in many cell lines 50 mg PK-CA577-1036-50MG click to select country
Actinomycin D Potent inducer of apoptosis in many cell lines 5 mg PK-CA577-1036-5MG click to select country
Actinomycin D (10 mM) Ready-to-use apoptosis inducer 50 µl PK-CA577-1036-50 click to select country
Anisomycin Activator of p54 and MAP kinases; induces apoptosis e.g. in the human monoblastoid cell line 10 mg PK-CA577-1549-10 click to select country
Apoptosis Inducer Set Contains 5 ready-to-use apoptosis inducers (Actinomycin D, Camptothecin, Cycloheximide, Dexamethasone, Etoposide) in a kit format 1 kit PK-CA577-K121-5 click to select country
AT-101 AT-101 is the R-(-) enantiomer of Gossypol that acts as an inhibitor of the anti-apoptotic Bcl proteins and an inducer of the pro-apoptotic proteins Noxa and Puma. 25 mg PK-CA577-2380-25 click to select country
AT-101 AT-101 is the R-(-) enantiomer of Gossypol that acts as an inhibitor of the anti-apoptotic Bcl proteins and an inducer of the pro-apoptotic proteins noxa and puma. 5 mg PK-CA577-2380-5 click to select country

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Product Name Description Size Catalog Number Information Prices
Berberine Chloride An isoquinoline alkaloid acts as an anti-cancer agent, inhibits cell growth and induces apoptosis in a variety of cancer cell lines. 100 mg PK-CA577-1830-100 click to select country
Berberine Chloride An isoquinoline alkaloid acts as an anti-cancer agent, inhibits cell growth and induces apoptosis in a variety of cancer cell lines. 500 mg PK-CA577-1830-500 click to select country
Betulinic acid Anti-tumor and anti-HIV agent that induces apoptosis 25 mg PK-CA577-1552-25 click to select country
Brefeldin A Induces apoptosis via caspase activation 5 mg PK-CA577-1560-5 click to select country

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Product Name Description Size Catalog Number Information Prices
C2 Ceramide A cell-permeable ceramide analog that induces apoptosis in a variety of cell types. 25 mg PK-CA577-2390-25 click to select country
C2 Ceramide A cell-permeable ceramide analog that induces apoptosis in a variety of cell types. 5 mg PK-CA577-2390-5 click to select country
Camptothecin Induces apoptosis e.g. in Jurkat, osteosarcoma and hepatoma cells 500 mg PK-CA577-1039-500MG click to select country
Camptothecin Induces apoptosis e.g. in Jurkat, osteosarcoma and hepatoma cells 50 mg PK-CA577-1039-50MG click to select country
Camptothecin (2 mM) Ready-to-use apoptosis inducer 1 ml PK-CA577-1039-1 click to select country
Carboplatin cis-Diammine(1,1-cyclobutanedicarboxylato) platinum 100 mg PK-CA577-1553-100 click to select country
Colchicine Induce apoptosis e.g. in PC-12 cells and cerebellar granule cells 1 g PK-CA577-1519 click to select country
Cycloheximide Induces apoptosis in a variety of cells but can also delay or inhibit apoptosis by other agents 1 g PK-CA577-1041-1G click to select country
Cycloheximide (100 mM) Ready-to-use apoptosis inducer 1 ml PK-CA577-1041-1 click to select country

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Product Name Description Size Catalog Number Information Prices
Daunorubicin.HCl Induces DNA single strand breaks and apoptosis e.g. in HeLaS3 tumor cells 10 mg PK-CA577-1524-10 click to select country
Dexamethasone Induces apoptosis e.g. in human thymocytes 10 g PK-CA577-1042-10G click to select country
Dexamethasone Induces apoptosis e.g. in human thymocytes 1 g PK-CA577-1042-1G click to select country
Dexamethasone (10 mM) Ready-to-use apoptosis inducer 1 ml PK-CA577-1042-1 click to select country
Doxorubicin.HCl Anti-tumor antibiotic that induces apoptosis 5 mg PK-CA577-1527-5 click to select country

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Product Name Description Size Catalog Number Information Prices
Etoposide Induces apoptosis e.g. in human T cells, mouse thymocytes, and HL-60 human leukemia cells 250 mg PK-CA577-1043-250MG click to select country
Etoposide Induces apoptosis e.g. in human T cells, mouse thymocytes, and HL-60 human leukemia cells 25 mg PK-CA577-1043-25MG click to select country
Etoposide (10 mM) Ready-to-use apoptosis inducer 100 µl PK-CA577-1043-100 click to select country

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Product Name Description Size Catalog Number Information Prices
Genistein Produces cell cycle arrest and apoptosis (>99% pure) 10 mg PK-CA577-1533-10 click to select country
Genistein Produces cell cycle arrest and apoptosis (>99% pure) 100 mg PK-CA577-1533-100 click to select country

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Product Name Description Size Catalog Number Information Prices
Ionomycin (Calcium salt) 5 mg PK-CA577-1566-5 click to select country
Ionomycin (free acid) Useful for studies of Ca2+ transport across biological membranes and measurement of cytoplasmic free Ca2+; induces apoptotic neuronal degeneration in embryonic cortical neurons (>90% pure) 5 mg PK-CA577-1565-5 click to select country

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Product Name Description Size Catalog Number Information Prices
LY573636 A potent anti-tumor agent, which causes growth arrest and apoptosis of a variety of human solid tumors in vitro and in vivo. 25 mg PK-CA577-2297-25 click to select country
LY573636 A potent anti-tumor agent, which causes growth arrest and apoptosis of a variety of human solid tumors in vitro and in vivo. 5 mg PK-CA577-2297-5 click to select country

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Product Name Description Size Catalog Number Information Prices
Mifepristone 11-(4-Dimethylamino)phenyl-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one, RU-486, RU-38486 50 mg PK-CA577-1561-50 click to select country
Mitomycin C Inhibitor of DNA synthesis, nuclear division. Induces apoptosis in cancer cells. 10 mg PK-CA578-M1108-10 click to select country
Mitomycin C Inhibitor of DNA synthesis, nuclear division. Induces apoptosis in cancer cells. 100 mg PK-CA578-M1108-100 click to select country
Mitomycin C Inhibitor of DNA synthesis, nuclear division. Induces apoptosis in cancer cells. 5 mg PK-CA578-M1108-5 click to select country

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Product Name Description Size Catalog Number Information Prices
Okadaic acid Induces apoptosis e.g. in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells, but inhibits glucocorticoid-induced apoptosis in T-cell hybridomas 25 µg PK-CA577-1543-25 click to select country

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Product Name Description Size Catalog Number Information Prices
Phorbol-12-myristate 13-acetate (PMA) Inhibits apoptosis induced by the Fas antigen, but induces apoptosis e.g. in HL-60 promyelocytic leukemia cells 5 mg PK-CA577-1544-5 click to select country
Phytosphingosine Phytosphingosine is a phospholipid structurally similar to Sphingosine that induces apoptosis in human T-cell lymphoma and non-small cell lung cancer cells. 250 mg PK-CA577-2426-250 click to select country
Phytosphingosine Phytosphingosine is a phospholipid structurally similar to Sphingosine that induces apoptosis in human T-cell lymphoma and non-small cell lung cancer cells. 50 mg PK-CA577-2426-50 click to select country

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Product Name Description Size Catalog Number Information Prices
Rapamycin Reported to induce apoptosis in a murine B cell line (>99% pure) 5 mg PK-CA577-1568-5 click to select country
Rapamycin Reported to induce apoptosis in a murine B cell line (>99% pure) 50 mg PK-CA577-1568-50 click to select country
Rosiglitazone Induces apoptosis in various cells, e.g. in vascular smooth muscle cells 100 mg PK-CA577-1559-100 click to select country
Rosiglitazone Induces apoptosis in various cells, e.g. in vascular smooth muscle cells 5 mg PK-CA577-1559-5 click to select country

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Product Name Description Size Catalog Number Information Prices
Staurosporine Potent apoptosis inducer 100 µg PK-CA577-1048-010 click to select country
Staurosporine Potent apoptosis inducer 1 mg PK-CA577-1048-1 click to select country
sTRAIL Receptor-1 (DR4), human, recombinant Recombinant Human soluble TNF Related Apoptosis Inducing Ligand Receptor 1 (DR4) 50 µg C-63601 click to select country

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Product Name Description Size Catalog Number Information Prices
Tamoxifen citrate Induces apoptosis e.g. in human malignant glioma cell lines 1 g PK-CA577-1551 click to select country
Thapsigargin Induces apoptosis in rat thymocytes and in human hepatoma cells (>99% pure) 1 mg PK-CA577-1558-1 click to select country
TL-1A, human, recombinant Recombinant Human TNF-like 1A (TNFSF15) 20 µg C-65065 click to select country
TRAIL (114-281 aa), human, recombinant Recombinant Human TNF-Related Apoptosis Inducing Ligand (Apo2L, 114-281 aa variant) 50 µg C-62600 click to select country
TRAIL (Apo2L), human, recombinant Recombinant Human Tumor Necrosis Factor-Related Apoptosis Inducing Ligand 50 µg C-63600 click to select country
TRAIL (Apo2L), mouse, recombinant Recombinant Mouse TRAIL (Tumor Necrosis Factor-Related Apoptosis Inducing Ligand) 50 µg D-63600 click to select country
TWEAK Receptor, human, recombinant Recombinant Human TNF-Related Weak Inducer of Apoptosis Receptor 25 µg C-63612 click to select country
Tyrphostin AG 1295 Specific and potent inhibitor of JAK2 protein tyrosine kinase, EGF receptor autophosphorylation, DNA synthesis and cell growth (>99%) 5 mg PK-CA577-1571-5 click to select country
Tyrphostin AG 490 Specific and potent inhibitor of JAK2 protein tyrosine kinase, EGF receptor autophosphorylation, DNA synthesis and cell growth (>99%) 5 mg PK-CA577-1570-5 click to select country